Researchers identify how cells cope with damage caused by cisplatin during chemotherapy treatment, revealing that lesions in the DNA caused by cisplatin lead to stalling of the transcription machine and subsequent removal of the lesion. Medscape Medical News
Outline issues and complications related to paroxysmal nocturnal hemoglobinuria (PNH), and review current and emerging treatment regimens for patients with PNH.
Functional approaches in development may enable physicians to rapidly identify factors that are important for the growth and survival of a particular leukemia and would serve as targets for therapy. Medscape Hematology-Oncology
For the first time, a significant prolongation of survival has been seen in this disorder, leading to calls for azacitidine to be offered to all high-risk patients. Medscape Medical News
Dr. Maurie Markman describes the somewhat controversial work of investigators who explored the relative role of chemotherapy vs. pelvic radiation in intermediate- or high-risk endometrial cancer. Medscape Hematology-Oncology