Patients with acute ischemic stroke requiring aggressive treatment to lower blood pressure (BP) should not be excluded from receiving thrombolytic therapy, according to findings reported in the September issue of the Archives of Neurology. Reuters Health Information
A phase 1 study of a neuroprotectant agent combining caffeine and ethanol suggests caffeinol can be given safely after tPA with some signal of improved outcome compared with historical controls. Medscape Medical News
Positive end-expiratory pressure designed to increase alveolar recruitment did not significantly lower mortality but did improve lung function and reduce the duration of organ failure. Medscape Medical News
A study shows that screening with a pulse carbon monoxide oximeter is a safe, easily applied tool at triage that can identify cases of unsuspected elevated levels of carbon monoxide. Medscape Medical News
The MENDS trial is one of the first studies to show that GABA-sparing agents for sedation are efficacious and safe in mechanically ventilated patients. Medscape Critical Care