In this expert interview, Dr. Gary Hudes addresses prognostication and individualization of targeted and other therapies for patients with renal cell carcinoma as well as management of known and emerging toxicities. Medscape Hematology-Oncology
Four antiangiogenesis drugs have been approved for human use in solid tumors but no validated biomarkers are available for routine clinical use. The roles and challenges of developing biomarkers of angiogenesis are reviewed. Nature Clinical Practice Oncology
Might an equivocal HER2 amplification result from a breast core biopsy specimen be consistently representative of the HER2 status of the overall breast tumor? What are the testing implications? American Journal of Clinical Pathology
In a large prospective study, higher circulating serum concentrations of 25-hydroxyvitamin D were associated with an increased risk for aggressive prostate cancer. Medscape Medical News
Functional polymorphisms in the gene expressing epidermal growth factor receptor (EGFR) have opposite prognostic implications for male and female patients with metastatic colon cancer, new study findings indicate. Reuters Health Information
Dramatic results showing that radioimmunotherapy with Zevalin prolongs progression-free survival by 2 years come just days after cuts in reimbursement for this therapy were announced in the United States. Medscape Medical News
