Brooks Cash, MD, provides an overview of our current understanding of the physiology of the GI tract with a view toward how that understanding may be applied to the treatment of chronic constipation. Medscape Gastroenterology
Higher blood levels of selenium were associated with aggressive prostate cancer, particularly in men with a certain variant of the superoxide dismutase gene. Medscape Medical News
Combining data on prostate-specific antigen, previous prostate biopsy results, family history of prostate cancer, and prostate size improves the prediction of risk for the disease. Medscape Medical News
Goserelin reduced the long-term risk for disease recurrence and death in premenopausal women with early breast cancer who did not take tamoxifen, and was found to be as effective as tamoxifen after 2 years of treatment. Medscape Medical News
Children diagnosed as having ADHD have a specific deficit in "top-down" attentional control that is likely a sign of a functional disconnection between the frontal and the occipital cortex in the brain. Medscape Medical News
The test identifies poor metabolizers of tamoxifen, who do less well on the drug and, in the case of postmenopausal women, who can be offered alternative therapy. Medscape Medical News