Reduced nephron number is hypothesized to be a risk factor for chronic kidney disease and hypertension. Whether reduced nephron number accelerates the early stages of diabetic nephropathy is unknown. Diabetes
Plasma creatinine may not reflect GFR especially in the early stages of CKD. Investigators try to improve the creatinine-based GFR estimation by including plasma cystatin C measurements. Kidney International
Six inflammatory and procoagulant biomarkers were correlated with kidney function measures in multi-ethnic patients to replicate results from similar studies in non-diverse populations. BMC Nephrology
Infusion of donor-derived transplant acceptance-inducing cells (TAICs) prior to kidney transplantation can prevent acute graft rejection in presensitized recipients and may allow for simpler immunosuppressive drug regimens, the results of a case report suggest. Reuters Health Information
Researchers from Japan have synthesized a novel angiotensin II receptor blocker (ARB) derivative, R-147176, that displays strong renal protective qualities with minimal blood pressure-lowering effects in animal experiments. Reuters Health Information
