This study evaluated the influence of two transfusion protocols on ABT requirements in patients undergoing hemiarthroplasty surgery for proximal humerus fracture. Transfusion Alternatives in Transfusion Medicine
In a phase 3 trial of terminally ill patients with opioid-induced constipation, 48% of methylnaltrexone-treated vs 15% of placebo-treated patients attained rapid laxation. Medscape Medical News
Do patients requiring prolonged acute mechanical ventilation have the same likelihood of being discharged alive as those on shorter-term mechanical ventilation? Critical Care Medicine
Dr Shorr reports on the NASCENT Trial which studied VAP in patients expected to undergo mechanical ventilation who received a silver-coated endotracheal tube. Medscape Pulmonary Medicine
Reduction in plasma melatonin levels and loss of circadian rhythm observed in critically ill patients receiving mechanical ventilation may contribute to this irregular sleep-wake pattern. Critical Care
