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Other links at Articles > Cardiology |
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Vytorin Rides Out Choppy SEAS
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The SEAS data were presented today at the European Society of Cardiology, but the focus turned to the cancer risks observed in the trial. An analysis of ongoing studies--IMPROVE-IT and SHARP--suggests the finding is a play of chance, but others, including prominent New England Journal of Medicine editorialists, say there is uncertainty about the safety and efficacy of the drug. Heartwire
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When Is Noninferior Superior to Superior?
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Testing against placebo (ie withholding therapy) in clinical trials is often unethical, so Dr Black explains why testing against an active comparator (another drug) means testing for "noninferiority".
Black on Cardiology
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