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Other links at Articles > Pathology and Lab Medicine |
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Resistance to Temozolomide in Leukemia Tied to DNA Repair Activity
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In pediatric patients with refractory or recurrent leukemia, temozolomide resistance is associated with activity of the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT), researchers report in the November 1st issue of the Journal of Clinical Oncology. Reuters Health Information
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Multiple Gene Variants Predispose to Methamphetamine Dependence
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Findings from genome-wide association studies in two separate populations indicate polygenic contributions to methamphetamine dependence from genes frequently associated with dependence on other addictive substances, investigators report in the Archives of General Psychiatry for March. Reuters Health Information
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Endomorphin-1 Plays Anti-Inflammatory Role in Arthritis
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The endogenous opioid endomorphin-1 plays an anti-inflammatory role in osteoarthritis, rheumatoid arthritis, and adjuvant-induced polyarthritis, according to a report in the February issue of Arthritis & Rheumatism. Reuters Health Information
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Genetic Polymorphism Linked With Stress-Induced Myocardial Ischemia
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A genetic polymorphism in the gene encoding beta1-adrenergic receptors (ADRB1) is associated with mental stress-induced myocardial ischemia in patients with coronary artery disease, according to a report in the April 14th Archives of Internal Medicine. Reuters Health Information
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