Optic neuritis and myelitis can occur as manifestations of "idiopathic" demyelinating syndromes, such as neuromyelitis optica and multiple sclerosis, as well as of systemic rheumatic syndromes. Knowledge of the distinguishing clinical and radiographic features is crucial for an accurate diagnosis. Nature Clinical Practice Rheumatology
Review the pathogenesis of progressive multiple sclerosis, and explore diagnostic and tactical tools that can enable better identification, monitoring, and treatment of the disease
