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Other links at Articles > Pathology and Lab Medicine |
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Genetic Loci Prone to Homozygosity Linked to Carcinomas
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Homozygosity at certain "hot spot" gene locations appears to play an important role in cancer susceptibility, scientists at the Cleveland Clinic Foundation report in the Journal of the American Medical Association for March 26. Reuters Health Information
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MMP Inhibitor-Bearing Virus Active Against Solid Tumors
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An oncolytic herpes virus "armed" with matrix metalloproteinase (MMP) inhibition may be effective for control of solid tumors, investigators report in the February 15th issue of Cancer Research. Reuters Health Information
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BRCA1 Mutations Promote Breast Cancer Through Effect on PTEN
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The results of a new study suggest that one way BRCA1 mutations promote breast cancer is by inactivating the PTEN tumor suppressor gene. The researchers are hopeful that the PTEN pathway can now serve as a therapeutic target for BRCA1 mutation-related cancers. Reuters Health Information
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Polymorphism Tied to Aggressive Prostate Cancer
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A single-nucleotide polymorphism (SNP) in the tumor suppressor gene DAB2IP appears to be associated with aggressive prostate cancer, US and Swedish researchers report in the December 19th issue of the Journal of the National Cancer Institute. Reuters Health Information
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