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Other links at Articles > Pathology and Lab Medicine |
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Resistance to Temozolomide in Leukemia Tied to DNA Repair Activity
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In pediatric patients with refractory or recurrent leukemia, temozolomide resistance is associated with activity of the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT), researchers report in the November 1st issue of the Journal of Clinical Oncology. Reuters Health Information
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Genetic Loci Prone to Homozygosity Linked to Carcinomas
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Homozygosity at certain "hot spot" gene locations appears to play an important role in cancer susceptibility, scientists at the Cleveland Clinic Foundation report in the Journal of the American Medical Association for March 26. Reuters Health Information
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Growth Protein May Provide New Target for Prostate Cancer
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Inhibition of the signal transducer and activator of transcription 5a/b (Stat5a/b), the key mediator of prolactin effects in prostate cancer cells, kills cancer cells and inhibits xenograft growth in mice, researchers report in the March 1st issue of Clinical Cancer Research. Reuters Health Information
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