An End-of-Life Care Task Force discusses how to better integrate palliative with standard care in patients at all stages of chronic and advanced respiratory tract illnesses or critical disease. Medscape Medical News
Reduction in plasma melatonin levels and loss of circadian rhythm observed in critically ill patients receiving mechanical ventilation may contribute to this irregular sleep-wake pattern. Critical Care
This study provides further support to the concept that achieving low triglyceride levels may be an additional consideration beyond LDL-C in patients after acute coronary syndrome. Journal of the American College of Cardiology
Does this study suggest that concerns should be put aside regarding the risk of death associated with the use of DES (relative to bare-metal stents) in diabetic patients? American Heart Journal
In a phase 3 trial of terminally ill patients with opioid-induced constipation, 48% of methylnaltrexone-treated vs 15% of placebo-treated patients attained rapid laxation. Medscape Medical News
The prevalence of clonal isolates, with a combined erm(B) and mef(A) genotype together with high-level macrolide and multidrug resistance, is increasing, and their spread may have health implications. Annals of Clinical Microbiology and Antimicrobials