The angiotensin receptor blocker was "noninferior" to the ACE inhibitor in this HOPE-like population, but the combination of the two drugs was associated with more adverse events without an increase in benefit. Heartwire
Presented with hypothetical treatment choices, many HF patients would sacrifice some days alive to feel better in the meantime; surprisingly, perhaps, a lot of those patients are only in the early stages of their disease. Heartwire
The use of combination therapy with ACEIs or ARBs may be preferable to diuretics in hypertensive patients with high cardiovascular risk and may provide protection against end-organ damage and serious cardiovascular events, in addition to BP control. Medscape Cardiology
Review the pathophysiologic mechanisms involved in acute coronary syndrome (ACS) and evaluate recent practice guidelines and emergent therapies for its treatment.
A cohort study showing an increased rate of hip bone loss suggests that the potential for bone loss should be considered when loop diuretics are prescribed to older patients in clinical practice. Medscape Medical News