DPYD, TYMS, and MTHFR polymorphisms play a limited role for FU-related toxicity, but a DPYD gene/sex-interaction is predictive for men; mode of administration and folinic acid coadministration are additional predictive factors. Medscape Medical News
Is there a new role for EGFR inhibitors in the treatment of lung cancer? In this expert column, Dr. Neil and Dr. Heist review the latest data. Medscape Hematology-Oncology
Dr. Anita Hill, who specializes in paroxysmal nocturnal hemoglobinuria (PNH) and in marrow failure, discusses the effects on quality of life of new therapies.