Tumors positive for human papillomavirus (HPV) have a better response to therapy, leading to significantly better survival than HPV-negative cancers. Medscape Medical News
Erythropoiesis-stimulating agents should continue to have an oncology indication, even though questions about their safety remain. Medscape Medical News
ESAs are no longer indicated for use in cancer patients for chemotherapy-induced anemia if the intent of chemotherapy is to cure the patient. Medscape Medical News
Research that will affect clinical practice includes a study showing that zoledronic acid reduces relapse in early breast cancer and KRAS mutations predict which patients will respond to cetuximab. Medscape Medical News
Maintenance therapy with zoledronic acid and thalidomide in patients with multiple myeloma does not increase the risk of renal impairment, according to a report posted on March 31st by BMC Clinical Pharmacology. Reuters Health Information
New research shows that high-dose methotrexate is the most effective drug for primary central nervous system lymphoma, with up to 20% of patients achieving a long-term remission with methotrexate alone. Medscape Medical News