The membrane-proximal ectodomain region (MPER) of the HIV-1 viral glycoprotein 41 (gp41) is a target of neutralizing antibodies and could become the focus of a potential vaccine, investigators at the Dana Farber Cancer Institute and Harvard Medial School in Boston report in the January issue of Immunity. Reuters Health Information
An investigational C1 esterase inhibitor (Berinert, CSL Behring, King of Prussia, PA) is "highly effective and well tolerated" for the treatment of acute abdominal and facial attacks in patients with hereditary angioedema (HAE). Reuters Health Information
Danazol reduces the frequency and severity of hereditary angioedema attacks, according to a report in the February Annals of Allergy, Asthma & Immunology. Reuters Health Information
A study shows that menopause is associated with lower lung function and more respiratory tract symptoms, especially among lean women. Medscape Medical News
A universal influenza immunization program implemented in Ontario, Canada, in 2000 appears to have reduced influenza-associated mortality and healthcare use, new research suggests. Reuters Health Information
In a randomized controlled, blinded study, maternal immunization with inactivated influenza vaccine was associated with a 63% reduction of laboratory-confirmed influenza in infants. Medscape Medical News