Whether human atheromata can regress is controversial. Animal model studies showing atheroma plaque shrinkage or reversal of atherosclerosis, and examples of plaque regression in humans are presented. Nature Clinical Practice Cardiovascular Medicine
Guidelines on the use of devices to regulate heart rhythm and rate have placed unprecedented emphasis on the need for optimal medical therapy before device therapy is considered. Medscape Medical News
In the Canadian SMART study, no safety concerns were noted about using large doses of candesartan cilexetil to treat proteinuria. Medscape Medical News