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Other links at Articles > Cardiology |
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New Papers on KIF6 and CHD Provoke Debate
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Three new papers attempt to replicate, in large prospective studies, findings published last year regarding a polymorphism--KIF6--that is believed to be associated with heart disease. The company funding the research--Celera--is so excited by the findings that it plans to launch a diagnostic test for KIF6. But an accompanying editorial says more work is needed to validate these findings. Heartwire
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Vytorin Rides Out Choppy SEAS
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The SEAS data were presented today at the European Society of Cardiology, but the focus turned to the cancer risks observed in the trial. An analysis of ongoing studies--IMPROVE-IT and SHARP--suggests the finding is a play of chance, but others, including prominent New England Journal of Medicine editorialists, say there is uncertainty about the safety and efficacy of the drug. Heartwire
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