|
|
Other links at Articles > Pathology and Lab Medicine |
| 1. |
Resistance to Temozolomide in Leukemia Tied to DNA Repair Activity
|
|
|
In pediatric patients with refractory or recurrent leukemia, temozolomide resistance is associated with activity of the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT), researchers report in the November 1st issue of the Journal of Clinical Oncology. Reuters Health Information
|
| 2. |
Genetic Loci Prone to Homozygosity Linked to Carcinomas
|
|
|
Homozygosity at certain "hot spot" gene locations appears to play an important role in cancer susceptibility, scientists at the Cleveland Clinic Foundation report in the Journal of the American Medical Association for March 26. Reuters Health Information
|
| 4. |
Schizophrenia-Linked Gene Tied to Bipolar Disorder
|
|
|
There is further evidence that a gene linked with schizophrenia - the disrupted-in-schizophrenia 1 (DISC1) gene -- is also associated with bipolar disorder, researchers report in the January issue of the Archives of General Psychiatry. Reuters Health Information
|
| 5. |
Stem Cell Transplant No Benefit After Relapse in Childhood Leukemia
|
|
|
Although event-free survival in children with standard-risk acute lymphoblastic leukemia (ALL) is now more than 80%, prognosis in those who relapse early continues to be poor, and is not improved with stem cell transplantation, according to researchers. Reuters Health Information
|
|
|