Corticosteroids enhance the activity of long-acting beta-2-agonists by slowing their distribution and elimination by airway smooth muscle cells, according to a report in the November issue of the Journal of Allergy and Clinical Immunology. Reuters Health Information
Neuroleptic-induced tardive dyskinesia can be safely and effectively treated with vitamin B6 (1200 milligrams daily), according to a double-blind, placebo-controlled, crossover study involving 50 inpatients with schizophrenia or schizoaffective disorder and tardive dyskinesia. Reuters Health Information
Adjuvant chemotherapy and tamoxifen treatment for primary breast cancer are both independently associated with reduced risks of contralateral breast cancer that persist for up to 10 and 5 years, respectively, after the first cancer diagnosis, according to a report in the Journal of the National Cancer Institute for January 2. Reuters Health Information
Among patients with rheumatoid arthritis (RA) in New Zealand, the rate of serious infection associated with leflunomide treatment is "acceptable in the context of optimally treating active RA," report Dr. Peter T. Chapman of Christchurch Hospital and colleagues in the November issue of the Journal of Rheumatology. Reuters Health Information
A less intensive chemotherapeutic regimen designed specifically for treating acute myeloid leukemia (AML) in patients with Down syndrome (DS) yields excellent outcomes, Japanese researchers have found. Reuters Health Information
Sorafenib, an agent with both antiangiogenic and antiproliferative activity, may represent a useful treatment for progressive hormone-refractory prostate cancer, new research suggests. Reuters Health Information
Recent updates on the use of tumor necrosis factor inhibitors for the management of rheumatoid arthritis and related conditions as illustrated by data from ACR 2007. Medscape Rheumatology
The dipeptidyl peptidase IV inhibitor vildagliptin (Galvus) is effective monotherapy for treatment-naive elderly patients with type 2 diabetes, according to a report in the December issue of Diabetes Care. Reuters Health Information
Dr. Cohen reviews the latest data on the efficacy and safety of TNF inhibitors in the treatment of RA -- an update from ACR 2007. Medscape Rheumatology
Dr. Levesque reviews our current knowledge on hematologic malignancies and anti-TNF-directed therapies in rheumatoid arthritis, an update from ACR 2007. Medscape Rheumatology