Pfizer Inc has won a U.S. court ruling that could limit the lawsuits claiming that its Celebrex painkiller caused heart attacks and strokes. Reuters Health Information
In daily clinical practice, anti-TNF therapy for patients with rheumatoid arthritis is less effective than that reported in randomized clinical trials (RCTs), Dutch researchers report in the November issue of Annals of the Rheumatic Diseases. However, patient selection influences results. Reuters Health Information
Water-soluble C60 fullerene prevents the degeneration of articular cartilage in a rabbit model of osteoarthritis (OA) through the downregulation of chondrocyte catabolic activity, according to Japanese researchers. Reuters Health Information
Genetically modified enterotoxigenic Escherichia coli (ETEC) vaccines safely induce mucosal immune responses without causing inflammation, according to a report in the November issue of Gut. Reuters Health Information
WellPoint Inc believes keeping its pharmacy benefit management business is the best way to extract value from the unit, but the health insurer will look at other options if such value is not achieved, its chief accounting officer said on Wednesday. Reuters Health Information
A meta-analysis of 4 randomized trials of the weight-loss drug rimonabant concurs with Food and Drug Administration findings of an increased risk for adverse psychiatric effects. Medscape Medical News
A growing body of evidence suggests that perioperative administration of gabapentin is efficacious and safe in the perioperative setting. British Journal of Anaesthesia
Erdosteine decreases the sputum viscoelastic properties and bacterial adhesion to the cell membrane, endowed with bronchial anti-inflammatory activity and a scavenging effect on free oxidant radicals. Expert Review of Respiratory Medicine
Linezolid appears to be a safe and effective treatment for step-down or compassionate use therapy in pediatric patients with drug-resistant Gram-positive bone and joint infections. Reuters Health Information
