Etanercept is effective for up to 192 weeks in patients with ankylosing spondylitis (AS), according to a report in the March issue of the Annals of the Rheumatic Diseases. Reuters Health Information
The beneficial effects of beta-adrenoceptor blockade on the failing heart may derive from their effects in the central nervous system (CNS), according to a report in the March 28th issue of Circulation Research. Reuters Health Information
Nelarabine alone, or particularly in combination with fludarabine, appears to be useful in the treatment of relapsed and refractory indolent leukemias, according to findings from a small phase I trial. Reuters Health Information
Pulmonary absorption of inhaled dihydroergotamine (DHE) mesylate, intended for treatment of acute migraine, produces plasma levels comparable to intravenous administration in healthy individuals, and is well-tolerated, investigators report in the March issue of Headache. Reuters Health Information
The atypical antipsychotic sertindole may prove effective in some patients who fail treatment with other antipsychotics, according to a report in the March issue BMC Psychiatry. Reuters Health Information
A system employing hospital levels of care delivered at home to elderly patients with chronic obstructive pulmonary disease (COPD) exacerbations provides results superior to those with inpatient treatment, according to Italian and US researchers. Reuters Health Information
Treatment with MC-1, a naturally occurring pyridoxine metabolite, does not reduce nonfatal MIs or cardiovascular deaths in intermediate- to high-risk patients undergoing coronary artery bypass grafting (CABG), the results of a randomized trial indicate. Reuters Health Information
In patients with ST-segment elevation MI (STEMI), treatment with tirofiban is at least as effective as abciximab in resolving ST-segment elevation at 90 minutes, and sirolimus-eluting stent implantation leads to better outcomes at 8 months compared with use of bare-metal stents. Reuters Health Information
Just one in five older adults who commit suicide are using antidepressants at the time of their death, according to a report in the May issue of the Journal of Epidemiology and Community Health. Reuters Health Information
In a retrospective study of heroin-dependent persons from Australia, researchers found that hospitalizations due to opioid use decreased significantly following treatment with naltrexone implants -- an outcome that was not observed in another cohort of patients who received traditional methadone maintenance treatment. Reuters Health Information