Nebivolol is as effective as metoprolol in the prevention of migraine attacks, but nebivolol is better tolerated and does not require as much dosage adjustment to reach therapeutic levels, researchers in Germany report. Reuters Health Information
A 5-day course of levofloxacin is at least as effective as a 10-day course of ciprofloxacin for treating acute pyelonephritis and complicated urinary tract infections (UTIs), note researchers from Ortho-McNeil Pharmaceuticals, which markets levofloxacin in the US as Levaquin. Reuters Health Information
Prophylaxis with botulinum toxin type A (BoNTA) or divalproex sodium (DVPX) significantly reduces disability related to episodic or chronic migraine, according to a report in the February issue of Headache. Reuters Health Information
Assessing the complex geriatric patient and working with decision support systems were discussed at the recent 2007 ASHP Midyear Clinical Meeting. Medscape Pharmacists
Pregabalin appears to be effective in the treatment of patients with trigeminal neuralgia, particularly in those without concomitant chronic facial pain, clinicians from Germany report in the February issue of Cephalalgia. Reuters Health Information
Review the spectrum of clinical syndromes that encompass hypertensive emergencies and focus on specific drugs and therapeutic strategies to optimize outcomes in the acute care setting.
For patients with advanced non-small-cell lung cancer (NSCLC) and a performance status (PS) of 2, combination chemotherapy is superior to erlotinib therapy as initial treatment, according to a report in the February 20th Journal of Clinical Oncology. Reuters Health Information
Enzastaurin, an oral serine/threonine kinase inhibitor, halted disease progression in some patients with metastatic non-small-cell lung cancer (NSCLC) in a single-arm, phase II study published in the March 1 issue of the Journal of Clinical Oncology. Reuters Health Information
Nimotuzumab enhances the antitumor activity of ionizing radiation in non-small-cell lung cancer (NSCLC) cell lines showing high or moderate expression of epidermal growth factor receptor (EGFR), according to a report in the February 26th issue of the British Journal of Cancer. Reuters Health Information
