Administration of the neurotransmitter orexin-A to monkeys counteracts the cognitive deficits and altered brain metabolism induced by sleep deprivation, new research findings show. Reuters Health Information
Studies in mice suggest that the central nervous system is able to reorganize itself after spinal cord injury (SCI) and use alternative pathways to bypass the injury to restore the cellular communication needed for movement. Reuters Health Information
Use of keratinocyte growth factor (palmiferin; delta-N23-KGF) prevents intra-alveolar edema in experimental lung isografts in rats, according to German investigators. Reuters Health Information
Although event-free survival in children with standard-risk acute lymphoblastic leukemia (ALL) is now more than 80%, prognosis in those who relapse early continues to be poor, and is not improved with stem cell transplantation, according to researchers. Reuters Health Information
Autologous hematopoietic stem cell transplantation improves survival and reduces skin thickening and other symptoms of systemic sclerosis, a team of European researchers reports in the January issue of the Annals of the Rheumatic Diseases. Reuters Health Information
Commercially available personal genome analyses may deliver too much too soon, in terms of current applications for disease prevention. Medscape Medical News
A team of scientists at Memorial Sloan-Kettering Cancer Center in New York has identified several endogenous human microRNAs that suppress breast cancer metastasis to lung and bone -- the two main sites of metastatic spread of breast carcinoma. Reuters Health Information
Patients who have experienced a stroke and are also carriers of APOE4 are at increased risk for dementia compared with subjects with just one of these factors or neither, according to a report in the January 1st issue of Neurology. Reuters Health Information
Injections of autologous bone marrow cells (BMC) directly into the endomyocardium of no-option patients with severe coronary artery disease (CAD) improves left ventricular ejection fraction and exercise tolerance, results of the international PROTECT-CAD trial show. Reuters Health Information
Examination of the molecular make-up of brain tumor cells from patients with glioblastoma multiforme (GBM) has shown that all specimens overexpress at least one of three specific proteins, which are therefore promising therapeutic targets, North Carolina-based researchers report in the January issue of Clinical Cancer Research. Reuters Health Information
