Statistically significant differences may not be clinically relevant. Are outcome event number and treatment effect size related in orthopedic randomized trials with statistically significant results? BMC Musculoskeletal Disorders
Inspiratory muscle training (IMT) can improve blood flow to both resting and exercising limbs in patients with chronic heart failure, according to a report in the Journal of the American College of Cardiology for April 29. Reuters Health Information
The results of a study published in the April 1st issue of the American Journal of Respiratory and Critical Care Medicine suggest that higher levels of systemic inflammation and left heart dysfunction are associated with reduced physical activity in patients with chronic obstructive pulmonary disease (COPD). Reuters Health Information
Older children with surgically repaired hypoplastic left heart syndrome have poorer exercise tolerance than their younger counterparts, researchers report in the April issue of the Journal of Pediatrics. Reuters Health Information
The authors advocate the use of NSAIDs in patients with debilitating musculoskeletal conditions, but recommend a cautious approach with close monitoring of patients at high-risk for CV events. Therapeutic Advances in Cardiovascular Disease
Spinal stenosis is treated preferentially with decompressive surgery but long-term outcomes are not good. Might a less invasive technique have improved long-term outcomes than traditional laminectomy? Spine