Osmotic disruption of the blood-brain barrier to enhance the effect of chemotherapy for central nervous system lymphoma is linked to maculopathy in two-thirds of patients who receive it, according to investigators at Hadassah-Hebrew University in Jerusalem, Israel. Reuters Health Information
Patients who develop age-related macular degeneration (AMD) before 75 years of age face a heightened risk of premature death due to cardiovascular events and stroke, investigators in Australia report in the British Journal of Ophthalmology published online on February 28. Reuters Health Information
The advent of anti-VEGF therapy has changed the way AMD is treated. Dr. Jay Duker discusses the evolving role of OCT in monitoring and treating AMD. Medscape Ophthalmology
Heat shock protein 90 (Hsp90) is overexpressed in several malignancies, and now an in vitro study by Canadian and Brazilian researchers has shown that Hsp90 overexpression is linked with a worse prognosis in patients with uveal melanoma. Reuters Health Information
This nomogram is a predictive tool, upon external validation, that can routinely be used to counsel patients in making treatment decisions. Annals of Surgery
Review the diagnosis and treatment of the major malignant tumors of the ocular adnexa, including the eyelid, conjunctiva, and orbit. Expert Review of Ophthalmology
When used for moderate-risk eye conditions, corneal grafts from donors over 65 can achieve 5-year survival rates similar to those of grafts from younger donors, according to the results of the Cornea Donor Study. Moreover, donor age as a continuous variable was not linked to graft failure. Reuters Health Information
