A daily dose of 1,000 IU vitamin D2 is as effective as 1,000 IU vitamin D3 in maintaining levels of serum 25-hydroxyvitamin D (25[OH]D), found this randomized, double-blind, placebo-controlled study. NAMS
Animal studies indicate that a genetic deficiency of an estradiol metabolite may underlie pre-eclampsia, and that the deficiency can be reversed. Reuters Health Information
Maternal and neonatal complications are worse in triplet and quadruplet pregnancies than twin pregnancies, according to a report in the April issue of the American Journal of Obstetrics & Gynecology. Reuters Health Information
Inferior vena cava (IVC) filter placement intended to prevent thromboembolic events seems safe during pregnancy for mother and fetus and "may be tentatively supported," clinicians from the UK report in the May issue of BJOG: An International Journal of Obstetrics and Gynecology. Reuters Health Information
Birth intervals of less than 18 months are associated with high risk of stillbirth and neonatal deaths, according to the results of a study from India. Reuters Health Information
Women who have a sister diagnosed with breast cancer remain at increased risk of breast cancer throughout their lives, epidemiologists in Sweden report in the Journal of the National Cancer Institute for May 21. Reuters Health Information
Letrozole is more effective than tamoxifen in preventing breast cancer relapse in postmenopausal women, even those in their 70s and 80s, according to results of the Breast International Group (BIG) 1-98 trial. Reuters Health Information
Clinicians from Korea report that the levonorgestrel-releasing intrauterine device (LNG-IUD) is an effective therapy for adenomyosis, or endometriosis, providing symptomatic relief and improvements in hematologic indices. Reuters Health Information
Diagnostic short-interval mammograms obtained to follow patients with "probably benign" lesions have a low sensitivity for detecting cancers diagnosed within the following 12 months, according to a paper in the May issue of the American Journal of Roentgenology. Reuters Health Information
How reliable is Web-based image review for clinically meaningful interpretive groups? Can cases that need prompt intervention or further evaluation be distinguished by triage from those that do not? American Journal of Clinical Pathology