Brachioradial pruritus may not be diagnosed for years despite significant chronic symptoms. The current case and review examine the diagnosis and management of this rare condition. Nature Clinical Practice Neurology
The first randomized controlled trial of this treatment shows that the ketogenic diet, which is a high-fat, carb restricted diet, can cut seizure rates by more than 50% in this patient group. Medscape Medical News
Progression of late infantile neuronal ceroid lipofuscinosis slows in children who receive viral vectors expressing the normal form of the mutant gene. Medscape Medical News
Optic neuritis and myelitis can occur as manifestations of "idiopathic" demyelinating syndromes, such as neuromyelitis optica and multiple sclerosis, as well as of systemic rheumatic syndromes. Knowledge of the distinguishing clinical and radiographic features is crucial for an accurate diagnosis. Nature Clinical Practice Rheumatology
Although there is no effective treatment to improve the clinical recovery from locked-in syndrome, the prompt diagnosis and initiation of neuropsychological testing can yield improved functional outcomes. The current case report highlights the best practice for patients with locked-in syndrome. Nature Clinical Practice Neurology
Giancarlo Comi, MD, presents the key findings from 2 pivotal trials in multiple sclerosis presented at AAN, PreCISe and BEYOND, and discusses their clinical implications. Medscape Neurology & Neurosurgery
Dr. Mark Tullman discusses results of key clinical trials presented at the 60th annual AAN meeting on currently available disease-modifying therapies for MS and the potential implications. Medscape Neurology & Neurosurgery
Dr Mark Tullman discusses data on emerging therapies for MS presented at the 60th Annual AAN Meeting and how these therapies may fill currently unmet needs in the pharmacologic management of MS. Medscape Neurology & Neurosurgery