Small molecule chloride-channel blockers slow cyst growth and preserve renal function in murine models of polycystic kidney disease, scientists report in the July issue of the Journal of the American Society of Nephrology, released online on April 2. Reuters Health Information
For the first time, researchers have evidence for an association between renal cell carcinoma (RCC) and multiple myeloma (MM) - one that "cannot be explained by random incidence alone," they say. Reuters Health Information
Black patients on hemodialysis are much more likely than their non-black counterparts to have high serum creatinine (sCr) levels, according to an article in the Clinical Journal of the American Society of Nephrology published online on April 16. Reuters Health Information
The aim of this study is to evaluate the association between acute serum creatinine changes in acute renal failure using the RIFLE criteria. BMC Nephrology
The multicenter FREEDOM examined steroid withdrawal vs avoidance in standard-risk renal transplant patients receiving CsA-ME, EC-MPS and basiliximab. American Journal of Transplantation
The first randomized controlled trial to examine the effectiveness, safety and tolerability of sirolimus to retard disease progression in ADPKD is designed and discussed. BMC Nephrology
Might microalbuminuria be measured effectively by a microfluidics-based assay using the P200 protein chip? What are the advantages and disadvantages of using this chip-based assay? American Journal of Clinical Pathology
In patients with chronic kidney disease, hyperphosphatemia stimulates vascular calcification by inducing the expression of osterix, an osteoblast transcription factor, in the neointima and tunica media, according to a report in the April 17th online issue of the Journal of the American Society of Nephrology. Reuters Health Information
Even the most up-to-date drugs do not prevent progression of chronic hypertensive kidney disease in most African Americans, according to a study in the Archives of Internal Medicine for April 28. Reuters Health Information