Lung transplantation in children with cystic fibrosis is not likely to prolong life and may do more harm than good, according to a retrospective analysis of essentially the entire U.S. experience with pediatric lung transplantation for cystic fibrosis for the period 1992 through 2002. Reuters Health Information
After a temporary rise in deaths among those on the waiting list, the new Model for End-Stage Liver Disease criteria have decreased the waiting list mortality rate as well as the amount of time patients spend waiting for a new liver. Medscape Medical News
A new Danish study shows that patients with venous thromboembolism have a substantially higher risk of subsequent myocardial infarction and stroke. The link could be direct or be the result of shared risk factors, the researchers say. Heartwire
Regimen-specific genomic signatures are able to predict response to chemotherapy regimens among patients with estrogen-receptor-negative breast cancer. Medscape Medical News
Compared with white women, minority women experience a higher level of cancer-associated pain and a higher degree of pain interference in their daily activities. Medscape Medical News
Variations in a gene involved in folate metabolism may explain some of the disparities in the incidence of colorectal cancer that have been seen among various racial/ethnic groups, new research suggests. Medscape Medical News
The antiepileptic drug lamotrigine, a popular treatment choice for women of childbearing age, has been linked to increased seizure activity during pregnancy, a new study suggests. Medscape Medical News
The FDA has approved revisions to the safety labeling for all classes of antidepressant medications and for lapatinib tablets (Tykerb). Medscape Medical News
A review shows that no monotherapy for rheumatoid arthritis is clearly superior but combination therapies improve response rates in some patients previously taking monotherapy. Medscape Medical News
