Mutations in the JAK2 gene appear to be associated with nearly 20% of cases of acute lymphoblastic leukemia in children with Down syndrome. Medscape Medical News
Levels of serum interleukin-7 can accurately predict the risk of graft-vs-host disease in patients undergoing an allogeneic hematopoietic stem-cell transplant. Medscape Medical News
In this audio program, experts detail the few currently available treatments for patients with metastatic melanoma and highlight new data emerging from trials of 3 promising new therapies. Medscape Hematology-Oncology
Results from the QUASAR trial show that adjuvant chemotherapy with fluorouracil improves survival in patients with stage 2 colorectal cancer, although the benefit is small. Medscape Medical News
An intensive immunochemotherapy regimen used in a Nordic study shows a plateau in survival curves that suggests a cure is in sight, say researchers. Medscape Medical News
The addition of the antisense agent oblimersen to fludarabine and cyclophosphamide improved response to therapy and survival in patients with relapsed or refractory chronic lymphocytic leukemia. Medscape Medical News
Understanding BRCA1 and BRAC2 associated risks in different populations is important in providing patients accurate risk information. Nature Reviews Cancer
