Long-term air pollution exposure is related to certain cancer deaths in recent studies. In this full cohort using another exposure assessment, are traffic-related air pollution and mortality related? Environmental Health Perspectives
Identification of sporadic mismatch repair (MMR)-defective tumors is central to improved prognostication. Can clinicopathologic criteria be used to select sporadic tumors for evaluation of MMR status? American Journal of Clinical Pathology
Seven genes that are responsible for tamoxifen resistance and tumor aggressiveness in estrogen-receptor-positive breast cancers have been identified. Medscape Medical News
Dr. Bradley A. Patay discusses several important papers reporting on the relationships of multiple genetic markers to prostate cancer. Medscape Pathology
Functional approaches in development may enable physicians to rapidly identify factors that are important for the growth and survival of a particular leukemia and would serve as targets for therapy. Medscape Hematology-Oncology
Results from a phase 3 trial showed no improvement in disease-free survival with cisplatin, and a significantly worse colostomy rate. Medscape Medical News