A combination of 4 novel urine biomarkers achieved a specificity and positive predictive value for prostate cancer that was more accurate than the PSA and the PCA3. Medscape Medical News
Although magnetic resonance imaging (MRI) of the breast provides advantages over mammography, and is increasingly used to evaluate candidates for breast-conservation treatment (BCT), it does not improve the outcome of BCT in women who have received radiation therapy for early-stage invasive breast carcinoma or ductal carcinoma in situ, according to a recent study. Reuters Health Information
The combination of permanent iodine-125 seed implants and carmustine (BCNU) wafers is safe and effective in patients with recurrent glioblastoma multiforme (GBM), according to a report in the February issue of the Journal of Neurosurgery. Reuters Health Information
In addition to stimulating the formation of erythrocytes, erythropoietin can enhance pathologic proliferation of blood vessel, and could affect patients with cancer and other conditions related to abnormal blood vessel growth. Medscape Medical News
Gene-expression profiling assays in early-stage breast cancer have shown potential in improving predictions of prognosis and treatment benefit, but more information is needed about how they are best incorporated into decision making about current breast cancer treatment. Medscape Medical News
The Common Terminology Criteria for Adverse Events was developed to standardize language for reporting adverse events that occur in NCI-sponsored clinical trials, but it is unable to adequately code the subacute adverse events that occur with new targeted therapies. Medscape Medical News
Tumors positive for human papillomavirus (HPV) have a better response to therapy, leading to significantly better survival than HPV-negative cancers. Medscape Medical News
In this Expert Interview from SABCS 2007, Dr. Clifford Hudis comments about adjuvant chemotherapy in breast cancer, with particular emphasis on when and for whom treatment should be offered. Medscape Hematology-Oncology
