Patients with chronic hepatitis C virus and advanced fibrosis or cirrhosis are at risk for disease progression and hepatic decompensation. Alimentary Pharmacology & Therapeutics
The FDA has approved revisions to the safety labeling for tadalafil tablets (Cialis), zaleplon capsules (Sonata), and eszopiclone tablets (Lunesta). Medscape Medical News
Use of pectin as a food thickener appears effective in reducing manifestations of gastroesophageal reflux disease (GERD) in children with cerebral palsy, Japanese researchers report in a paper published on April 16th in BMC Gastroenterology. Reuters Health Information
Patients who experience daily gastric acid reflux have lower blood pressure than those who experience fewer GERD episodes or none, according to study findings published April 15th by BMC Gastroenterology. Reuters Health Information
Potentially fatal hepatotoxicity can be triggered by sulfasalazine therapy for rheumatoid arthritis, according to a series of case reports investigated by UK researchers. Reuters Health Information
Similar to evidence from studies conducted in the west, an inverse association between body mass index (BMI) and the risk of squamous cell carcinoma of the esophagus has been shown in a population-based study conducted in China. Reuters Health Information
Patients diagnosed with premalignant gastric lesions are at significant risk of gastric cancer, according to results of a nationwide cohort study in the Netherlands. Reuters Health Information
The results of a study published in the April issue of the American Journal of Gastroenterology suggest that the combination of traditional nonsteroidal anti-inflammatory drugs (NSAID) and acetaminophen increases the risk of gastrointestinal bleeding compared with the use of either agent alone. Reuters Health Information
The results of a Swedish population-based twin study provide evidence that postmenopausal estrogen hormone therapy (HT) increases the risk of gastroesophageal reflux symptoms, independent of heredity, body weight, and tobacco use. Reuters Health Information
New research shows that a mutation responsible for hereditary nonpolyposis colon cancer (Lynch syndrome) originated centuries earlier and is more prevalent than previously believed. Reuters Health Information