Studies in mice provide evidence that endogenous cannabinoids are involved in the development of alcohol-induced fatty liver disease and that blocking these proteins might help fight alcoholic fatty liver disease. Reuters Health Information
Treatment with the combination of cisplatin, epirubicin, L-leucovorin, and 5-fluorouracil, referred to as the PELF regimen, has little or no effect on overall or disease-free survival in patients with completely resected gastric cancer, Italian researchers report. Reuters Health Information
Oxaliplatin-based chemotherapy administered before and after resection of liver tumors secondary to colorectal cancer improves progression-free survival compared with tumor resection alone, according to the results of a multinational trial. Reuters Health Information
An unbuffered acidic region in the gastric cardia present during the postprandial period is larger in patients with severe reflux disease than in healthy subjects, often extending to the border of the gastroesophageal junction, a UK research team reports. Reuters Health Information
In the majority of patients, surgical reintervention after initial antireflux surgery for gastroesophageal reflux disease (GERD) yields good results, according to Dutch researchers. Reuters Health Information
Combination chemotherapy with oxaliplatin and docetaxel is effective and well tolerated in patients with advanced gastric cancer, according to a report in the February 12th issue of the British Journal of Cancer. Reuters Health Information
Is there a difference in the utilization of current pharmacologic therapies for colorectal cancer between older and younger patients? Medscape Hematology-Oncology
This video roundtable discussion focuses on how to prolong PFS and reduce toxicities in patients with advanced colorectal cancer by creatively and flexibly applying available drugs and combinations. Medscape Hematology-Oncology
William Sandborn, MD, reviews the data on maintenance therapy for ulcerative colitis, which is indicated to prevent symptomatic and endoscopic relapse and to minimize the risk for colectomy and CRC. Medscape Gastroenterology
