The FDA has approved sapropterin dihydrochloride tablets (Kuvan), pantoprazole sodium delayed-release oral suspension (Protonix), and a low-dose tablet formulation of lopinavir/ritonavir (Kaletra). Medscape Medical News
A meta-analysis of 8 published clinical trials shows no benefit from anthracyclines in patients with HER2-negative breast cancer, sparing them toxic effects of the drugs. Medscape Medical News
In a prospective trial, multidisciplinary treatment aided patients in all stages of back pain chronicity, suggesting that this should not be given only to those with lower grades of chronic pain. Medscape Medical News
The FDA has approved the sale of a generic version of Zyrtec without a prescription. Also today, restless leg syndrome is linked to stroke and heart disease.
In a study on aggressive behavior during childhood temper tantrums, researchers identify 5 red flags that possibly indicate a psychiatric disorder and need for a referral to a specialist. Medscape Medical News
Pediatric cancer patients have higher rates of morphologic abnormalities, including asymmetric lower limbs and curvature of the spine, which suggests that the genetic defect causing the abnormality might also be associated with the cancer. Medscape Medical News
In a study of 89 pregnant women with bipolar disorder, stopping mood stabilizers during pregnancy doubled the risk for a new mood episode. Medscape Medical News
In a trial of insomnia, treatment with zolpidem extended release was associated with sustained improvements in sleep onset and maintenance and next-day concentration and decreased morning sleepiness. Medscape Medical News