Rosuvastatin calcium (Crestor) is a safe and effective agent for long-term treatment of patients with severe hypercholesterolemia, according to a clinical trial sponsored by AstraZeneca. Reuters Health Information
Vitamin E supplementation reduces the incidence of myocardial infarction (MI) among older patients with type 2 diabetes who produce a less active form of the antioxidant protein haptoglobin (Hp). Reuters Health Information
This article describes the features and management of the type B insulin resistance syndrome, which should be considered in patients with increasing hyperglycemia despite high-dose insulin treatment. Nature Clinical Practice Endocrinology & Metabolism
Higher than expected variation of creatine kinase (CK) activity within the population suggests that the upper reference limit should be increased, according to a report in the October American Heart Journal. Reuters Health Information
A case-control study shows that insulin-sensitizing treatment with metformin is not related to a higher incidence of bone fractures; current treatment with insulin increases the risk for fractures. Medscape Medical News
Adiposity in late adolescent girls may have a negative effect on bone strength, based on peripheral quantitative computed tomography assessment, researchers report. Reuters Health Information
A novel growth hormone precursor improves cardiovascular risk profiles without increasing glucose levels, and reduces visceral abdominal fat without affecting subcutaneous fat, in HIV-infected men on antiretroviral drugs, according to a report in The New England Journal of Medicine for December 6. Reuters Health Information
Insulin treatment of nondiabetic patients with acute coronary syndrome (ACS) and hyperglycemia is associated with reduced risk of death in the first 30 days, according to a report in the December issue of Heart. Reuters Health Information
The cholesterol ester transfer protein (CETP) TaqIB polymorphism is associated with the risk of sudden death in type 2 diabetic patients, according to French researchers. Reuters Health Information
Administration of dehydroepiandrosterone (DHEA) ameliorates the oxidative imbalance prevalent in patients with type 2 diabetes, according to a report in the November Diabetes Care. Reuters Health Information