Insulin resistance in certain islet cell antibody (ICA)-positive relatives of patients with type 1 diabetes appears to accelerate onset of the disease, researchers report in the January issue of Diabetes Care. Reuters Health Information
In patients with type 2 diabetes requiring insulin, adjunctive treatment with the amylin analog pramlintide at mealtimes leads to further improvement in glycemic control and weight, in the clinical experience of a group of Louisiana clinicians. Reuters Health Information
Puberty is associated with a reduction in insulin responsiveness in adolescents with type 1 diabetes receiving aspart insulin via pump therapy. However, puberty appears to have no significant influence on pharmacokinetics, researchers report in the January issue of Diabetes Care. Reuters Health Information
Patients hospitalized for acute ischemic stroke who are undernourished at admission are likely to remain so during their hospital stay, putting them at risk for poorer outcomes, a study suggests. Medscape Medical News
In men with prostate cancer, androgen-deprivation therapy (ADT) appears to increase the risk of subsequent diabetes, according to researchers. Reuters Health Information
A study shows that low serum concentration of vitamin E, a marker of poor nutrition, is associated with subsequent decline in physical function among community-living older adults. Medscape Medical News
The sickle cell gene is carried by 1 in 12 African Americans. Management of the endocrine and metabolic disorders related to sickle cell disease (SCD) and testing for iron overload in SCD are reviewed. Nature Clinical Practice Endocrinology & Metabolism
In a preliminary study, patients who had gastric banding surgery lost more weight and had a higher likelihood of diabetes remission than did patients who used conventional methods for weight loss and diabetes control. Medscape Medical News
Regardless of gender, children with newly diagnosed primary hypertension show increased fat tissue mass and decreased bone strength. Reuters Health Information
Patients with type 1 hereditary hemochromatosis, associated with a homozygous mutation in the HFE gene, can benefit from phlebotomy and hence iron depletion, Italian researchers report in the January issue of Diabetes Care. Reuters Health Information