Severe chronic kidney disease poses a problem of selecting chemotherapy. Liposomal doxorubicin was found to be safe and effective in treating a patient with advanced ovarian cancer. The Medscape Journal of Medicine
A 57-year-old man presents to the emergency department (ED) with severe acute-onset abdominal pain in the right lower portion of his abdomen, along with progressive bloating, nausea, vomiting, night sweats, and low-grade fever. He has experienced intermittent abdominal discomfort with constipation and a 30-lb weight loss over the past 2-3 months. He has not been able to have a bowel movement on the day of presentation. There is a palpable mass in his right lower quadrant. What is the diagnosis? eMedicine Case Presentations
National guidelines continue to err on the side of caution when it comes to screening cancer patients. Experts are debating the pros and cons. Medscape Medical News
COX-2 may be of significance to the development and proliferation of bladder transitional cell carcinoma, consistent with a potential role for COX-2 inhibitors in prevention and management. The Medscape Journal of Medicine
Understanding donor, recipient, and allograft factors that come together to define the high-risk transplant recipient is a necessary prerequisite to providing optimal patient care. Medscape Transplantation
An infusion of milrinone, a phosphodiesterase inhibitor that combines vasodilating and inotropic properties, reverses the cerebral vasospasm that can accompany an aneurysmal subarachnoid hemorrhage (aSAH), French researchers report in the March issue of Stroke. Reuters Health Information
Short-term treatment with a renal assist device (RAD), comprised of a conventional hemofiltration cartridge lined with monolayers of nonautologous renal tubule cells, substantially improves survival in patients with acute renal failure when added to conventional dialysis. Reuters Health Information
