Results of a phase 2 trial using tPA beyond 3 hours in patients with mismatch on diffusion- and perfusion-weighted imaging are negative for the primary outcome of lower infarct growth, but show some positive trends in secondary end points. Medscape Medical News
A study shows that screening with a pulse carbon monoxide oximeter is a safe, easily applied tool at triage that can identify cases of unsuspected elevated levels of carbon monoxide. Medscape Medical News
Blood pressure lowering in the 60% to 70% of patients who become hypertensive immediately following acute stroke reduces 3-month mortality without serious adverse effects or increasing stroke severity, a randomized pilot study suggests. Medscape Medical News
Review treatment options for patients with renal cell carcinoma, including combination and sequential drug therapies that may help improve patient outcome.
A 46-year-old woman presents to the emergency department (ED) with constant right upper quadrant pain that radiates to her back and side. She underwent a laparoscopic cholecystectomy 2 weeks ago, without complications. Imaging shows dilated segments of bowel with a characteristic appearance. What is the diagnosis? eMedicine Case Presentations
In a randomized controlled trial of patients with septic shock, low-dose vasopressin did not reduce mortality rates vs norepinephrine. Medscape Medical News
Erythropoietin and darbepoetin, often used to treat chemotherapy-associated anemia, may cause serious complications such as venous thromboembolism or even death. Medscape Medical News
A new study has found a disturbing variation between the prescribed dose of radiation and the actual amount delivered to tumors. Researchers are calling for new guidelines to address this problem. Medscape Medical News
During hospitalization for acute exacerbation of chronic obstructive pulmonary disease (COPD), increased circulation of cardiac-specific troponin T (cTnT) is a strong and independent prognostic factor for mortality after discharge, a research team in Norway has discovered. Reuters Health Information
