Post hoc analysis of data from the SPARCL trial shows no significant difference in recurrent stroke reduction with atorvastatin treatment between younger and older subgroups. Medscape Medical News
A new study shows that the risk for stroke increases with use of antipsychotic drugs and might be even higher in patients taking atypical antipsychotics or in patients with dementia. Medscape Medical News
The addition of apixaban to antiplatelet therapy resulted in an increase in bleeding, but there was also an observed trend toward a reduction in clinically relevant ischemic events, a new dose-ranging study has shown. Heartwire
Descendants of hematopoietic progenitor cells that were genetically engineered to express apolipoprotein AI (apoAI) counter the accumulation of cholesterol on artery walls, according to a study in mice by researchers from Vanderbilt University reported in the August issue of Arteriosclerosis, Thrombosis, and Vascular Biology. ApoAI is the major protein component of high-density lipoprotein. Reuters Health Information
Compared to implantation of paclitaxel-eluting stents, the use of sirolimus-eluting stents reduces restenosis and has other beneficial effects in patients with diabetes, a group who have an increased risk of unfavorable outcomes with bare-metal stents, Korean researchers report in the August 26th issue of the Journal of the American College of Cardiology. Reuters Health Information
Frequent intensive hemodialysis has recently gained increasing popularity. Medscape speaks with Philip A. McFarlane, MD, about the use of intensive hemodialysis and its effect on patient outcomes. Medscape Nephrology
Explore the epidemiology of sudden death in patients on dialysis, the most appropriate therapies for established coronary artery disease (CAD) in these patients, the effects of different phosphate binders, and the role of screening for coronary artery disease in asymptomatic CKD patients.