The genetic variant on chromosome 9p21 that is linked to an increased risk of MI has now been shown to increase the risk of abdominal aortic aneurysm and intracranial aneurysm. This gives some valuable insight into the mechanisms behind these three diseases, say the researchers. Heartwire
The FDA has approved revisions to the safety labeling for imatinib mesylate tablets (Gleevec), levetiracetam injection (Keppra), and filgrastim injection (Neupogen). Medscape Medical News
An abnormal ECG in a young, highly trained athlete might represent the initial expression of underlying cardiomyopathy, a new study suggests, and might not simply be the benign expression of cardiac remodeling associated with athletic conditioning. Heartwire
A study confirms that patients with stable coronary artery disease and a diagnosis of depression or anxiety face a higher risk for cardiac events. Medscape Medical News
Both physical activity and moderate alcohol intake are important to lower the risk for fatal ischemic heart disease and all-cause mortality, a study shows. Medscape Medical News
An analysis from the Cholesterol Treatment Trialists indicates that statins reduce the risk for major vascular events and mortality, even in people with diabetes and no vascular disease at baseline. Medscape Medical News
A large, prospective, longitudinal study suggests metabolic syndrome is an independent vascular risk factor that doubles stroke risk among women and Hispanics. Medscape Medical News
The results of the long-awaited and controversial ENHANCE trial, finally announced today, have shown no benefit of the combination of ezetimibe and simvastatin over simvastatin alone. Heartwire
The American College of Physicians has issued updated guidelines on palliative care of pain, dyspnea, and depression at the end of life. Medscape Medical News
Increasing evidence points to insulin resistance as a primary etiologic factor in the development of nonischemic
heart failure. What are the specific potential therapeutic approaches? Journal of the American College of Cardiology
