Hospitals with higher complex medical and surgical case volumes are assumed to be more likely to implement evidence-based processes of care. But is this really the case? International Journal for Quality in Health Care
Pharmacy benefit management companies appeared to pay pharmacies much less per generic-drug transaction than the companies charged employer groups for the same transaction. American Journal of Health-System Pharmacy
Many clinical trial groups do not have the resources to establish and use software systems to manage trial data in compliance with ICH guidelines. Is an open-source approach feasible and appropriate? PLoS Medicine
The US FDA has issued a "not-approvable" letter to the Medicines Company for an additional dosing regimen of the drug covering upstream treatment of ACS initiated in the emergency department, based on the ACUITY trial. Heartwire
The state of Connecticut sued McKesson Corp on Wednesday on charges that the drug wholesaler violated anti-racketeering laws by conspiring to artificially inflate the wholesale prices used to determine payments by private and public insurance plans. Reuters Health Information
A new focus on drug safety is delaying the approval of some medicines as regulators impose requirements meant to minimize side effects, a top U.S. drug regulator told Reuters on Tuesday. Reuters Health Information
After 15 years, Collins, who presided over the successful completion of the Human Genome Project, needs the time and opportunity to pursue other professional activities. Medscape Medical News